How to accept things as-is and live according to as-is?

In the search for meaning and purpose of life, it seems that Buddhism is silent on this issue that many modern people are concerned with. The way to reconcile seems to be "accept things as it is". However, I personally know people who have trouble living without a "meaning of life". They ask themselves questions like "Why do I need to do this? Why can't I do that instead?". They are not nonconformist, but just does not see the point of doing anything at all. These thoughts can actually lead some of them to become suicidal as a form of release. What does Buddhism teach about how lack of meaning of life can make someone so negative, and the method, procedures and way of thinking that can help people to "accept things as it is"? Notes to my personal understanding to help with better quality answers. - "Meaning of Life" and "Purpose of Life" are not necessarily the one and same thing. - Not finding the meaning/purpose does not mean it doesn't exist **Clarification:** I am not blaming Buddhism for "lack of meaning/purpose of life", although some of those troubled people *claim* to be Buddhists themselves. Instead, I am exploring the *real* Buddhist way of managing this anxiety. In other beliefs and religion, the meaning is prescribed and the troubled people find peace in that. But my views are similar to the Buddhist view, so I hope to find a way to cope without resorting to those religions or "artificial comfort".