is pus and blood najis

I bursted a pimple on my thigh and rubbed on that pus and blood till the blood and pus were not visible. Then wore the pant and undergarments. Do my clothes and pants become najis of small amount of left over blood and pus if it sticks to the clothes? And if I burst a pimple and blood and pus comes out of the pimple, does it invalidate my wudu?